doi: 10.7763/IJAPM.2012.V2.94
Evaluation of Protoporphyrine IX-Light Emitting Diode Based Antimicrobial Photodynamic Therapy against Staphylococcus Aureus
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S.Ganesan
1
- 1 the Department of Medical Physics, Anna University, Chennai 600025, India
- 2 the Centre for Advanced Studies in Botany, University of Madras, Chennai 600005.
Abstract
The antimicrobial photodynamic activity of protoporphyrine IX (PPIX) in conjunction with red light - emitting diode (LED) and xenon lamp was carried out against <i>Staphylococcus aureus (S.aureus)</i>. At 30min illumination using the red LED and 30μM of PPIX 99.8% reduction of <i>S.aureus</i> survival was achieved. Based on optofluorometric study, it is further observed that the measurement of steady-state native fluorescence of amino acid, tryptophan provided a method to monitor the Antimicrobial photodynamic therapy (APDT) efficiency by optical means.
Keywords
- Antimicrobial photodynamic therapy
- red LED
- protoporphyrine IX
How to Cite
Fathi Awad, C.Ramprasath, N.Mathivanan, P. Aruna, and S.Ganesan, "Evaluation of Protoporphyrine IX-Light Emitting Diode Based Antimicrobial Photodynamic Therapy against Staphylococcus Aureus," International Journal of Applied Physics and Mathematics, vol. 2, no. 3, pp. 218-220, 2012. https://doi.org/ 10.7763/IJAPM.2012.V2.94
Copyright & License
Copyright © 2012 by the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).